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LY 272015 hydrochloride
CAS No. 172895-15-7
LY 272015 hydrochloride( —— )
Catalog No. M33881 CAS No. 172895-15-7
LY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 64 | Get Quote |
|
| 5MG | 123 | Get Quote |
|
| 10MG | 198 | Get Quote |
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| 25MG | 409 | Get Quote |
|
| 50MG | 655 | Get Quote |
|
| 100MG | 1017 | Get Quote |
|
| 200MG | 1368 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLY 272015 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionLY 272015 hydrochloride is an orally active and selective 5-HT2B receptor antagonist that displays antihypertensive effects in DOCA-salt hypertensive rats.
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DescriptionLY-272015 hydrochloride is an orally active, specific 5-HT2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number172895-15-7
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Formula Weight372.89
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Molecular FormulaC21H25ClN2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 5 mg/mL (13.41 mM; Ultrasonic (<60°C)
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SMILESCl.O(C1=CC=C(C=C1OC)CC2NCCC=3C=4C=C(C=CC4NC32)C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. S W Watts, et al. 5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats. Am J Physiol. 1999 Mar;276(3):H944-52.?
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